E2F-1 (Acetyl Lys120) Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA24384-50, RA24384-100
Citations, Manuals and MSDS Available upon request.
Background: E2F transcription factor 1 (E2F1) Homo sapiens The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can media
Condition: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Storage Instructions: -20°C/1 year
Recommended dilutions: WB: 1:500-10000 ELISA: 1:10000
Alternative Names: E2F1 RBBP3
Applications: WB; ELISA
Species Cross-Reactivity: Human:K120; Mouse:K115; Rat:K118
GeneID (Human): 1869
Protein MW (KDa): 70
SWISS: Q01094
Source: Rabbit
Research Use Only