EP4 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA24589-50, RA24589-100
Citations, Manuals and MSDS Available upon request.
Background: prostaglandin E receptor 4 (PTGER4) Homo sapiens The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2) . This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Alternative Names: PTGER4; PTGER2; Prostaglandin E2 receptor EP4 subtype; PGE receptor EP4 subtype; PGE2 receptor EP4 subtype; Prostanoid EP4 receptor
Applications: WB; IF/ICC; ELISA
Species Cross-Reactivity: Human; Rat; Mouse
GeneID (Human): 5734
Protein MW (KDa): 55
SWISS: P35408
Source: Rabbit
Research Use Only