ERK 5 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: RA21090-50, RA21090-100
Citations, Manuals and MSDS Available upon request.
Condition: PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Store at: -20°C/1 year
Recommended Dilutions: WB: 1:1000-2000 IHC:1:200-500
Purification Technology:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Names: MAPK7; BMK1; ERK5; PRKM7; Mitogen-activated protein kinase 7; MAP kinase 7; MAPK 7; Big MAP kinase 1; BMK-1; Extracellular signal-regulated kinase 5; ERK-5; YM3369
Background: mitogen-activated protein kinase 7(MAPK7) Homo sapiens The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq, Jul 2008],
Applications: WB, IHC-p, IF (paraffin section)
Species Cross-Reactivity: Human, Mouse, Rat
Molecular Weight: 89-115
Protein Molecular Weight (kDa): 89-115
GeneID (Human): 5598
SWISS: Q13164
Source: Rabbit
Immunogen: Recombinant Protein of ERK 5
Category: Polyclonal
Research Use Only