ET-1 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA24724-50, RA24724-100
Citations, Manuals and MSDS Available upon request.
Background: endothelin 1 (EDN1) Homo sapiens This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Alternative Names: EDN1; Endothelin-1; Preproendothelin-1; PPET1
Applications: WB; IHC-p; IF (paraffin section) ; ELISA
Species Cross-Reactivity: Human; Rat; Mouse
GeneID (Human): 1906
Protein MW (KDa): 25
SWISS: P05305
Source: Rabbit
Research Use Only