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ETO-2 Polyclonal Antibody - RA24731

ETO-2 Polyclonal Antibody - RA24731

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ETO-2 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA24731-50, RA24731-100 Citations, Manuals and MSDS Available upon request. Background: CBFA2/RUNX1 translocation partner 3 (CBFA2T3) Homo sapiens This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t (16;21) (q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010], Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions: -20°C/1 year Recommended dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. Alternative Names: CBFA2T3; MTG16; MTGR2; ZMYND4; Protein CBFA2T3; MTG8-related protein 2; Myeloid translocation gene on chromosome 16 protein; hMTG16; Zinc finger MYND domain-containing protein 4 Applications: IHC-p; IF (paraffin section) ; ELISA Species Cross-Reactivity: Human; Mouse GeneID (Human): 863 SWISS: O75081 Source: Rabbit Research Use Only