FAS-L Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA24881-50, RA24881-100
Citations, Manuals and MSDS Available upon request.
Background: Fas ligand (FASLG) Homo sapiens This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE) . Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: IHC-p 1:50-200, ELISA 1:10000-20000
Alternative Names: Tumor necrosis factor ligand superfamily member 6 (Apoptosis antigen ligand;APTL;CD95 ligand;CD95-L;Fas antigen ligand;Fas ligand;FasL;CD antigen CD178) [Cleaved into: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form (Receptor-binding FasL ectodomain;Soluble Fas ligand;sFasL) ; ADAM10-processed FasL form (APL) ; FasL intracellular domain (FasL ICD;SPPL2A-processed FasL form;SPA) ]
Applications: IHC-p; IF (paraffin section) ; ELISA
Species Cross-Reactivity: Human; Rat; Mouse
GeneID (Human): 356
SWISS: P48023
Source: Rabbit
Research Use Only