FGD1 Rabbit pAb
Sizes: 50µl, 100µl
Catalogue Numbers: RA32313-50, RA32313-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.256% sodium azide.
Store at: -20°C/1 year
Recommended Dilutions: WB 1:500-2000
Purification Technology:The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Alternative Names: FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF) (Zinc finger FYVE domain-containing protein 3)
Background: This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of faciogenital dysplasia and X-linked mental retardation, syndromatic 16.[provided by RefSeq, Mar 2011],
Applications: WB
Species Cross-Reactivity: Human, Mouse
Molecular Weight: 105
Protein Molecular Weight (kDa): 105
GeneID (Human): 2245
SWISS: P98174
Source: Rabbit
Immunogen: Synthesized peptide derived from human FGD1
Category: Polyclonal
Research Use Only