FGFR1/2/3/4 (Phospho-Tyr653+Tyr654) Rabbit pAb
Sizes: 50µl, 100µl
Catalogue Numbers: RA36826-50, RA36826-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, and 0.142% sodium azide.
Store at: -20°C/1 year
Recommended Dilutions: WB 1:500-2000
Purification Technology:The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Alternative Names: Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Background: fibroblast growth factor receptor 1(FGFR1) Homo sapiens The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome,
Applications: WB
Species Cross-Reactivity: Human, Mouse, Rat
GeneID (Human): 2260
SWISS: P11362
Source: Rabbit
Immunogen: Synthesized peptide derived from human FGFR1/2/3/4 (Phospho-Tyr653+Tyr654)
Category: Polyclonal
Research Use Only