FH Monoclonal Antibody (7F1)
Sizes: 50μL, 100μL
Catalogue Number: RA11208-50, RA11208-100
Citations, Manuals and MSDS Available upon request.
Condition: PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Store At/In: -20°C/1 year
Recommended Dilutions: WB: 1:3000 IF 1:200 IHC 1:50-300
Alternative Names: Fumarate hydratase, mitochondrial (Fumarase) (EC 4.2.1.2)
Background: fumarate hydratase(FH) Homo sapiens The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq, Jul 2008],
Applications: WB; IHC-p; IF/ICC
Species Cross-Reactivity: Human; Mouse; Rat
Molecular Weight: 50
GeneID (Human): 2271
Protein MW (KDa): 50
SWISS: P07954
Source: Mouse
Research Use Only