Fibulin-5 Monoclonal Antibody
Size: 50μL, 100μL
Catalogue Numbers: RA11215-50, RA11215-100
Citations, Manuals and MSDS Available upon request.
Background: fibulin 5 (FBLN5) Homo sapiens The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3) . [provided by RefSeq, Jul 2008],
Condition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.
Storage Instructions: -20°C/1 year
Applications: WB; IHC-p; IF (paraffin section) ; ELISA
Species Cross-Reactivity: Human
GeneID (Human): 10516
SWISS: Q9UBX5
Source: Mouse
Research Use Only