Frizzled-7 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA20683-50, RA20683-100
Citations, Manuals and MSDS Available upon request.
Background: frizzled class receptor 7 (FZD7) Homo sapiens Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Alternative Names: FZD7; Frizzled-7; Fz-7; hFz7; FzE3
Applications: WB; IF/ICC; ELISA
Species Cross-Reactivity: Human; Mouse
GeneID (Human): 8324
Protein MW (KDa): 64
SWISS: O75084
Source: Rabbit
Research Use Only