GA45B Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA32399-50, RA32399-100
Citations, Manuals and MSDS Available upon request.
Background: growth arrest and DNA damage inducible beta (GADD45B) Homo sapiens This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. [provided by RefSeq, Jul 2008],
Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000
Applications: WB; ELISA
Species Cross-Reactivity: Human; Mouse
GeneID (Human): 4616
Protein MW (KDa): 17
SWISS: O75293
Source: Rabbit
Research Use Only