Girdin Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA25325-50, RA25325-100
Citations, Manuals and MSDS Available upon request.
Background: coiled-coil domain containing 88A (CCDC88A) Homo sapiens This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K) -dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: WB 1:500-2000 ,Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Alternative Names: CCDC88A; APE; GRDN; KIAA1212; Girdin; Akt phosphorylation enhancer; APE; Coiled-coil domain-containing protein 88A; G alpha-interacting vesicle-associated protein; GIV; Girders of actin filament; Hook-related protein 1; HkRP1
Applications: IHC-p; IF (paraffin section) ; ELISA
Species Cross-Reactivity: Human; Mouse
GeneID (Human): 55704
SWISS: Q3V6T2
Source: Rabbit
Research Use Only