SHP-1 mouse mAb
Sizes: 50µl, 100µl
Catalogue Numbers: RA11982-50, RA11982-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Store at: -20°C/1 year
Recommended Dilution: wb dilution 1:1000
Purification Technology: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Alternative Names: 70 kda SHP1L protein , 70Z-SHP , EC 3.1.3.48 , HCP , HCPH , Hematopoietic cell phosphatase , Hematopoietic cell protein tyrosine phosphatase , Hematopoietic cell protein-tyrosine phosphatase , HPTP1C , Protein tyrosine phosphatase 1C , Protein tyrosine phosphatase non receptor type 6 , Protein tyrosine phosphatase SHP1 , Protein-tyrosine phosphatase 1C , protein-tyrosine phosphatase SHP 1 , Protein-tyrosine phosphatase SHP-1 , PTN6_HUMAN , PTP 1C , PTP-1C , PTP1C , PTPN6 , SH PTP 1 , SH PTP1 , SH-PTP1 , SHP 1 , SHP 1L , SHP1 , SHP1L , tyrosine protein phosphatase non receptor type 6 , Tyrosine-protein phosphatase non-receptor type 6.
Background: protein tyrosine phosphatase, non-receptor type 6 (PTPN6) Homo sapiens The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jul
Applications: WB, IP
Species Cross-Reactivity: Human
GeneID (Human): 5777
SWISS: P29350
Source: Mouse
Immunogen: Purified recombinant human SHP-1 protein fragments expressed in E.coli.
Category: Monoclonal
Research Use Only