3β-HSD7 rabbit pAb
Sizes: 50μL, 100μL
Catalogue Numbers: ES1548-50, ES1548-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008],
Alternate Name: HSD3B7; 3 beta-hydroxysteroid dehydrogenase type 7; 3 beta-hydroxysteroid dehydrogenase type VII; 3-beta-HSD VII; 3-beta-hydroxy-Delta (5)-C27 steroid oxidoreductase; C (27) 3-beta-HSD; Cholest-5-ene-3-beta; 7-alpha-diol 3-beta-dehydrogenase
Source: Rabbit
Applications: WB; ELISA
Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Reactivity: Human; Mouse; Rat
Immunogen: The antiserum was produced against synthesized peptide derived from human HSD3B7. AA range:121-170
Storage and Stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band (KD): 41kD
Human Gene ID: 80270
Human SWISS Prot NO: Q9H2F3
Subcellular Location: Endoplasmic reticulum membrane; Multi-pass membrane protein.
Research Use Only