5T4 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A19541-20, A19541-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein.
Synonyms: 5T4; M6P1; 5T4AG; WAIF1
GeneID: 7162
Swiss-Prot: Q13641
Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB
Calculated Molecular Weight: 46kDa
Observed Molecular Weight: 75kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 321-420 of human 5T4 (Q13641).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Research Areas: Cancer, Tumor immunology, Tumor-associated antigens, Cell Biology Developmental Biology, Immunology Inflammation, Stem Cells
Recommended Dilutions: WB: 1:500 - 1:1000
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Plasma Membrane,
Positive Samples: A549, MCF7
Keywords: TPBG, 5T4, 5T4AG, M6P1, WAIF1, trophoblast glycoprotein, trophoblast glycoprotein|5T4 oncofetal antigen|5T4 oncofetal trophoblast glycoprotein|5T4 oncotrophoblast glycoprotein|wnt-activated inhibitory factor 1, Q13641
Symbol: TPBG
Category: Monoclonal Antibodies
Research Use Only