Aldehyde dehydrogenase 5-A1/SSADH/ALDH5A1 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A24829-20, A24829-100
Citations, Manuals and SDS Available upon request.
Background: This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.
Synonyms: SSDH; SSADH; Aldehyde dehydrogenase 5-A1/SSADH/ALDH5A1?
GeneID: 7915
Swiss-Prot: P51649
Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB, IHC-P, IF/ICC
Calculated Molecular Weight: 57kDa
Observed Molecular Weight: 54kDa
Immunogen: Recombinant Protein corresponding to a sequence within amino acids 777-976 of human Aldehyde dehydrogenase 5-A1/SSADH/ALDH5A1(NP_001071.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Research Areas: Signal Transduction, Endocrine Metabolism, Mitochondrial metabolism, Mitochondrial markers, Amino acid metabolism, Lipid Metabolism, Neuroscience
Recommended Dilutions: WB: 1:1000 - 1:5000 | IHC-P: 1:50 - 1:200 | IF/ICC: 1:50 - 1:200
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Mitochondrion
Positive Samples: Caco-2, Mouse liver
Keywords: 7915, sc-70004, sc-70007, sc-130684, ALDH5A1, SSADH, SSDH, aldehyde dehydrogenase 5 family member A1, succinate-semialdehyde dehydrogenase, mitochondrial, NAD(+)-dependent succinic semialdehyde dehydrogenase, mitochondrial succinate semialdehyde dehydrogenase, P51649, Aldehyde Dehydrogenase 5 Family Member A1, NAD(+)-Dependent Succinic Semialdehyde Dehydrogenase, Succinate-Semialdehyde Dehydrogenase, Mitochondrial, Mitochondrial Succinate Semialdehyde Dehydrogenase, Aldehyde Dehydrogenase 5 Family, Member A1, Aldehyde Dehydrogenase Family 5 Member A1, EC 1.2.1.24, sc 70004, sc 70007, sc 130684, sc70004, sc70007, sc130684, DHTX, p63, UVRAG, Aldehyde dehydrogenase 5-A1/SSADH/ALDH5A1?
Symbol: ALDH5A1
Category: Monoclonal Antibodies
Research Use Only