Bmi-1 Rabbit Polyclonal Antibody(F270)
Sizes: 50µl, 100µl
Catalogue Numbers: RA22428-50, RA22428-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Store at: -20°C/1 year
Recommended Dilutions: WB 1:500-2000
Purification Technology:The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Alternative Names: Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51); YM3799
Background: BMI1 proto-oncogene, polycomb ring finger(BMI1) Homo sapiens This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. [provided by RefSeq, Sep 2015],
Applications: WB
Species Cross-Reactivity: Human
Molecular Weight: 37-43
Protein Molecular Weight (kDa): 37-43
GeneID (Human): 100532731
SWISS: P35226
Source: Rabbit
Immunogen: Recombinant Protein derived from human Bmi-1
Category: Polyclonal
Research Use Only