Calpain 1 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A8710-20, A8710-100
Citations, Manuals and SDS Available upon request.
Background: The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene.
Synonyms: CANP; muCL; CANP1; SPG76; CANPL1; muCANP; Calpain 1
GeneID: 823
Swiss-Prot: P07384
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 82kDa
Observed Molecular Weight: 75kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Calpain 1 (P07384).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IF/ICC
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 -1:1000 | IF/ICC: 1:50 -1:200
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Apoptosis, Ubiquitin, Immunology Inflammation, T Cell Receptor Signaling Pathway, Neuroscience, Calcium Signaling, Neurodegenerative Diseases, Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: U-937, Mouse kidney
Cellular Location: Cell Membrane, Cytoplasm
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.