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$551.27 USD
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CALIXAR’s CALXGLUK is a calixarene detergent that can be used to solubilize membrane protein as GPCR.  


Compound name: CALXGLUK

Catalogue number: CALXGLUK_10MG, CALXGLUK_50MG, CALXGLUK_100MG

Molec. Formula: C71H95N9O22

CAS: nd

MW: 1426.5 g/mol

pKa: na

Percent Composition: C, 59.78; H, 6.71; N, 8.84; O, 24.67 


Physical state: Beige powder

Purity (HPLC, 214nm): <95%

Retention time (RP18 HPLC)b: tR = 13.4 min

CMC: 0.025 mM

Exact mass​: 1425.6592

Stability: Store in <-20°C freezer for up to one year

Solubility Structure: Soluble in water (2.5mM), methanol and DMSO



CALIXAR practices a custom-made approach 

CALIXAR’s CALXGLUK is a very gentle detergent used to stabilize native membrane proteins. CALXGLUK is non-ionic and hence is not sensitive to ionic strength or pH fluctuations is well adapted to stabilize many different specific membrane proteins.

Calixar’s CALXGLUK can help deliver lipid detergent mixed micelles and protein detergent micelles. CALXGLUK also provides for the stabilization of native and functional membrane proteins within a solution.

Our CALXGLUK is provided in a powder form and is used in an aqueous solution or buffer which can also be mixed within biological substances (biological membranes).

CALXGLUK is a non-ionic calixarene based detergent / surfactant with three polar glucose groups and a heptyl chain.


CALIXAR’s CALXGLUK is non-ionic and therefore is not sensitive to ionic strength or pH variations and is able to stabilize specific membrane proteins. Due to the fluorinated chain, CALXGLUK does not solubilize lipid membranes.


CALIXAR’s CALXGLUK is a high-quality detergent / reagent utilized for research, drug discovery projects, and structural studies. Our technology is adapted for use in pharmaceutical and biotechnology companies, as well as for life science ​academic teams (biochemists, structural biologists, pharmacologists, virologists).


  • Antibodies (including nanobodies, scaffold proteins, aptamers)
  • Small molecules
  • 3D Structures (cryoEM, XRay crystallography, NMR, SANS, SAXS)
  • Drug discovery (Screening: HTS, FBDD, SBDD; Hit and lead validation)
  • Antibody discovery (Immunization and display technologies)
  • Clinical stage (drug validation on reliable native DDLAC)



Synthesis of amphiphilic calixarene glycoside detergents and use of same for extracting and stabilizing native functional membrane proteins