CaMKII Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A25000-20, A25000-100
Citations, Manuals and SDS Available upon request.
Background: The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene.
Synonyms: CAMKA; MRD53; MRT63; CaMKIIalpha; CaMKIINalpha; CaMKII
GeneID: 815/ 816/ 817/ 818
Swiss Prot: Q9UQM7/Q13554/Q13557/Q13555
Tested Applications: ELISA, WB
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 54kDa/72kDa/56kDa/62kDa
Observed Molecular Weight: 50-60kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200-300 of human CaMKII (NP_741960.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IP: 0.5μg-4μg antibody for 400μg-600μg extracts of whole cells
Research Areas: Neuroscience；Neurotransmission；Calcium Signaling；Calmodulin / CaMKSignal；Transduction；Protein Phosphorylation；Ser / Thr Kinases；Other Kinases；Signal Transduction；Signaling Pathway；Calcium Signaling；Calmodulin Pathway
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: U-87 MG, Neuro-2a, C6
Keywords: CAMKA, MRD53, MRT63, CaMKIIalpha, CaMKIINalpha, CaMKII
Symbol: CAMK2A/CAMK2B/CAMK2D/CAMK2G
Category: Monoclonal Antibodies
Research Use Only