Casein Kinase 1 alpha (CSNK1A1) Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A9308-20, A9308-100
Citations, Manuals and SDS Available upon request.
Background: Enables protein serine/threonine kinase activity. Involved in several processes, including negative regulation of canonical Wnt signaling pathway; peptidyl-serine phosphorylation; and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Located in centrosome; cytosol; and nuclear speck. Part of beta-catenin destruction complex. Colocalizes with keratin filament and mRNA cleavage and polyadenylation specificity factor complex. Biomarker of Alzheimer's disease and inclusion body myositis.
Synonyms: CK1; CK1a; CKIa; HLCDGP1; PRO2975; HEL-S-77p; Casein Kinase 1 alpha (CSNK1A1)
GeneID: 1452
Swiss-Prot: P48729
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 39kDa
Observed Molecular Weight: 35kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 238-337 of human Casein Kinase 1 alpha (CSNK1A1) (P48729).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000 | IHC-P: 1:50 - 1:200
Research Areas: Signal Transduction, Kinase, Serine threonine kinases, Cell Biology Developmental Biology, Wnt ��-Catenin Signaling Pathway, Stem Cells
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HeLa, NIH/3T3, Jurkat, Mouse lung, Rat lung, Rat brain
Cellular Location: Chromosome, Cytoplasm, Nucleus speckle, centromere, Centrosome, Cytoskeleton, Kinetochore, Microtubule Organizing Center, Cilium Basal Body
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.