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Caspase-1 Rat mAb - A21085

Caspase-1 Rat mAb - A21085

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Caspase-1 Rat mAb

Sizes: 20µl, 100µl

Catalogue Numbers: A21085-20, A21085-100

Citations, Manuals and SDS Available upon request.

Background: Enables cysteine-type endopeptidase activity. Involved in several processes, including positive regulation of I-kappaB kinase/NF-kappaB signaling; positive regulation of interleukin-1 beta production; and protein autoprocessing. Acts upstream of or within several processes, including membrane hyperpolarization; mitochondrial depolarization; and positive regulation of interleukin-1 alpha production. Located in extracellular region. Part of IPAF inflammasome complex. Is expressed in knee joint and metanephros. Orthologous to human CASP1 (caspase 1).

Synonyms: ICE; Il1bc

GeneID: 12362

Swiss-Prot: P29452

Reactivity: Mouse, Rat

Tested Applications: ELISA, WB

Calculated Molecular Weight: 46kDa

Observed Molecular Weight: 48kDa/33kDa

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 206-220aa of mouse Caspase-1.

Immunogen Species: Mouse

Host: Rat

Isotype: IgG

Purity: Affinity purification

Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.

Research Areas: Cancer, Invasion and Metastasis, Signal Transduction, ErbB-HER Signaling Pathway, Cell Biology & Developmental Biology, Apoptosis, Caspases, Endocrine & Metabolism, Immunology & Inflammation, Neuroscience, Neurodegenerative Diseases

Recommended Dilutions: WB: 1:500 - 1:1000

Modifications: Unmodified

Conjugate: Unconjugated

Cellular Location: Cytoplasm

Positive Samples: Mouse lung, Mouse spleen, Rat lung

Keywords: 834,sc-22164,sc-22163,sc-1780,sc-515,sc-622,CASP 1,CASP1,Caspase 1,Caspase 1/p20/p10,Caspase1,ICE,IL 1 beta converting enzyme,IL 1BC,IL1BC,IL1BCE,Interleukin 1 beta convertase,p10,p20,P45,caspase 1,caspase-1,CASP1 nirs variant 1,IL-1 beta-converting enzyme,IL1B-convertase,apoptosis-related cysteine peptidase,interleukin 1,beta,convertase,interleukin 1-B converting enzyme,P29466,Apoptosis-Related Cysteine Peptidase,Interleukin 1,Beta,Convertase,IL-1 Beta-Converting Enzyme,Caspase-1,Apoptosis-Related Cysteine Peptidase (Interleukin 1,Convertase),Apoptosis-Related Cysteine Protease (Interleukin 1,Interleukin-1 Beta-Converting Enzyme,Interleukin 1-B Converting Enzyme,Interleukin-1 Beta Convertase,CASP1 Nirs Variant 1,IL1B-Convertase,EC 3.4.22.36,CASP-1,IL-1BC,sc22164,sc 22164,sc22163,sc 22163,sc1780,sc 1780,sc515,sc 515,sc622,sc 622,免疫,炎症,天然免疫,感染,病毒,自身免疫,炎症小体,焦亡,NLRP3,NLR

Symbol: Casp1

Category: Monoclonal Antibodies

Research Use Only