Caspase-6 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A22437-20, A22437-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms.
Synonyms: MCH2; CSP-6; caspase-6; Caspase-6
GeneID: 839
Swiss Prot: P55212
Tested Applications: ELISA, IHC-P
Reactivity: Mouse, Rat
Calculated Molecular Weight: 33kDa
Observed Molecular Weight: Refer to figures
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 150-250 of human Caspase-6 (P55212).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: IHC-P: 1:50 - 1:200
Research Areas: Signal Transduction, ErbB-HER Signaling Pathway, Cell Biology Developmental Biology, Apoptosis, Caspases, Inhibition of Apoptosis, Death Receptor Signaling Pathway, Neuroscience, Neurodegenerative Diseases, Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Cytoplasm
Keywords: 839, sc-22177, sc-1230, sc-1232, sc-1231, sc-23380, sc-130714, sc-15381, Apoptotic protease Mch 2, CASP 6, CASP6, Caspase 6, Caspase 6/p18/p11, Caspase6, MCH2, caspase 6, caspase-6, apoptotic protease MCH-2, apoptosis-related cysteine peptidase, apoptosis-related cysteine protease, P55212, Apoptosis-Related Cysteine Peptidase, Apoptosis-Related Cysteine Protease, Apoptotic Protease MCH-2, Apoptotic Protease Mch-2, EC 3.4.22.59, Caspase-6, CASP-6, Caspase-6 p18, TNF
Symbol: CASP6
Category: Monoclonal Antibodies
Research Use Only