Caspase-6 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A24004-20, A24004-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms.
Synonyms: MCH2; CSP-6; caspase-6; Caspase-6
GeneID: 839
Swiss-Prot: P55212
Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB
Calculated Molecular Weight: 33kDa
Observed Molecular Weight: 35kDa
Immunogen: A synthesized peptide derived from human Caspase-6.
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Research Areas: Signal Transduction, ErbB-HER Signaling Pathway, Cell Biology Developmental Biology, Apoptosis, Caspases, Inhibition of Apoptosis, Death Receptor Signaling Pathway, Neuroscience, Neurodegenerative Diseases, Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease
Recommended Dilutions: WB: 1:500 - 1:2000
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Cytoplasm
Positive Samples: Jurkat, MCF7, RAW 264.7, C6
Keywords: 839, sc-22177, sc-1230, sc-1232, sc-1231, sc-23380, sc-130714, sc-15381, Apoptotic protease Mch 2, CASP 6, CASP6, Caspase 6, Caspase 6/p18/p11, Caspase6, MCH2, caspase 6, caspase-6, apoptotic protease MCH-2, apoptosis-related cysteine peptidase, apoptosis-related cysteine protease, P55212, Apoptosis-Related Cysteine Peptidase, Apoptosis-Related Cysteine Protease, Apoptotic Protease MCH-2, Apoptotic Protease Mch-2, EC 3.4.22.59, Caspase-6, CASP-6, Caspase-6 p18, TNF
Symbol: CASP6
Category: Monoclonal Antibodies
Research Use Only