CD11b/ITGAM Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A19010-20, A19010-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms: CR3A; MO1A; CD11B; MAC-1; MAC1A; SLEB6; CD11b/ITGAM
GeneID: 3684
Swiss Prot: P11215
Tested Applications: ELISA, WB, IHC-P, FC
Reactivity: Human
Calculated Molecular Weight: 127kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1053-1152 of human CD11b/ITGAM (P11215).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IHC-P: 1:50 - 1:200 | FC: 1:50 - 1:200
Research Areas: Signal Transduction, G protein signaling, G-Protein-Coupled Receptors Signaling to MAPK Erk, PI3K-Akt Signaling Pathway, MAPK-Erk Signaling Pathway, Cell Biology Developmental Biology, Cell Adhesion, Cytoskeleton, Immunology Inflammation, CDs, Neuroscience, Cell Type Marker, Stem Cells, Hematopoietic Progenitors, Mesenchymal Stem Cells
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Membrane, Single-pass Type I Membrane Protein,
Keywords: 3684, sc-6612, sc-28664, sc-23937, CD11B, CR 3 alpha chain, CR3A, Integrin alpha M, ITGAM, MAC 1, MAC1A, MO1A, Neutrophil adherence receptor, SLEB6, MAC-1, integrin subunit alpha M, integrin alpha-M, CD11 antigen-like family member B, CR-3 alpha chain, antigen CD11b (p170), cell surface glycoprotein MAC-1 subunit alpha, complement component 3 receptor 3 subunit, integrin, alpha M (complement component 3 receptor 3 subunit), leukocyte adhesion receptor MO1, macrophage antigen alpha polypeptide, neutrophil adherence receptor alpha-M subunit, P11215, Integrin Subunit Alpha M, Integrin, Alpha M (Complement Component 3 Receptor 3 Subunit), Cell Surface Glycoprotein MAC-1 Subunit Alpha, Complement Component 3 Receptor 3 Subunit, CD11 Antigen-Like Family Member B, Leukocyte Adhesion Receptor MO1, CR-3 Alpha Chain, Alpha M (Complement Component Receptor 3, Alpha, Also Known As CD11b (P170), Macrophage Antigen Alpha Polypeptide), Neutrophil Adherence Receptor Alpha-M Subunit, Macrophage Antigen Alpha Polypeptide, Neutrophil Adherence Receptor, Antigen CD11b (P170), Integrin Alpha-M, CD11b Antigen, CD11b/ITAM, integrin alpha-MCD11 antigen-like family member BCR-3 alpha chainantigen CD11b (p170)cell surface glycoprotein MAC-1 subunit alphacomplement component 3 receptor 3 subunitintegrin, alpha M (complement component 3 receptor 3 subunit)leukocyte adhesion receptor MO1macrophage antigen alpha polypeptideneutrophil adherence receptor alpha-M subunit, CD11b/ITGAM, 病理诊断抗体, 病理诊断抗体, 病理诊断抗体, 病理诊断, 病理诊断抗体, 病理诊断
Symbol: ITGAM
Category: Monoclonal Antibodies
Research Use Only