CLCN4 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A13790-20, A13790-100
Citations, Manuals and SDS Available upon request.
Background: The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. This gene is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3. The physiological role of chloride channel 4 remains unknown but may contribute to the pathogenesis of neuronal disorders. Alternate splicing results in two transcript variants that encode different proteins.
Synonyms: CLC4; ClC-4; MRX15; MRX49; ClC-4A; MRXSRC; CLCN4
GeneID: 1183
Swiss Prot: P51793
Tested Applications: ELISA, WB
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 85kDa
Observed Molecular Weight: 85kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 600-700 of human CLCN4 (NP_001821.2).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000
Research Areas: Cancer, Signal Transduction, Endocrine Metabolism, Neuroscience
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: U-87MG, LO2, Mouse brain, Rat brain
Cellular Location: Early Endosome Membrane, Late Endosome Membrane, Multi-pass Membrane Protein,
Keywords: 1183, CLCN4, CLC4, ClC-4, ClC-4A, MRX15, MRX49, chloride voltage-gated channel 4, H(+)/Cl(-) exchange transporter 4, chloride channel 4, chloride channel protein 4, chloride channel, voltage-sensitive 4, chloride transporter ClC-4, P51793, Chloride Voltage-Gated Channel 4, Chloride Channel, Voltage-Sensitive 4, Chloride Channel Protein 4, Chloride Transporter ClC-4, Chloride Channel 4, H(+)/Cl(-) Exchange Transporter 4
Symbol: CLCN4
Category: Polyclonal Antibodies
Research Use Only