Collagen IV Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A24008-20, A24008-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. This particular collagen IV subunit, however, is only found in a subset of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Mutations in this gene are associated with type II autosomal recessive Alport syndrome (hereditary glomerulonephropathy) and with familial benign hematuria (thin basement membrane disease). Two transcripts, differing only in their transcription start sites, have been identified for this gene and, as is common for collagen genes, multiple polyadenylation sites are found in the 3' UTR.
Synonyms: BFH; ATS2; BFH1; CA44; Collagen IV
GeneID: 1286/1288/1284/1282
Swiss-Prot: P53420/Q14031/P08572/P02462
Reactivity: Human,Mouse,Rat
Tested Applications: ELISA, WB,DB
Calculated Molecular Weight: 164kDa
Observed Molecular Weight: 170-185kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1573-1690 of human COL4A4（NP_000083.3）.
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Research Areas: Collagen, Signal Transduction
Recommended Dilutions: WB: 1:500 - 1:1000 | DB: 1:500 - 1:1000
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Secreted
Positive Samples: HeLa
Keywords: BFH, ATS2, CA44, Collagen IV
Symbol: COL4A4/COL4A6/COL4A2/COL4A1
Category: Monoclonal Antibodies
Research Use Only