Catalogue number: DLAC _250MG
Molec. Formula: C22H43NO11
MW: 497.6 g/mol
Percent Composition: C, 53.1; H, 8.71; N, 2.81; O, 35.37
Physical state: White powder
Purity (HPLC, 214nm): 97%
Retention time (RP18 HPLC)b: R = 10.6 min
CMC: 1.3 mM
Exact mass: 497.2836
Stability: Store in <-20°C freezer for up to one year
Solubility Structure: Soluble in water (65mM), methanol and DMSO
CALIXAR uses a unique & custom-established procedure
CALIXAR’s DLAC is provided to clients in a powder form and is used in aqueous solutions or buffers. DLAC can be processed with biological materials (biological membranes).
Clients are able to use DLAC to better produce lipid detergents, mixed micelles, and protein detergent micelles. DLAC provides our clients with a way to extract, to solubilize and to stabilize native and functional membrane proteins.
DLAC is a quite mild detergent to extract, to solubilize and to stabilize native membrane proteins. As DDLAC is non-ionic. Therefore, it is not sensitive to ionic strength or pH variations which is ideal to extract, to solubilize and to stabilize specific membrane proteins of high medical relevance.
CALIXAR’s DLAC is non-ionic and therefore not susceptible to ionic strength or pH variations. It is specifically built to extract, solubilize and stabilize precise membrane proteins.
CALIXAR’s DLAC (N-decylamine lactobionamide) extracts high-quality membrane proteins utilized for research, drug discovery projects and structural studies. They are used by pharmaceutical firms, biotechnology companies, and academic teams (biochemists, structural biologists, pharmacologists, virologists) that are committed to the life science disciplines.
- Antibodies (including nanobodies, scaffold proteins, aptamers)
- Small molecules
- 3D Structures (cryoEM, XRay crystallography, NMR, SANS, SAXS)
- Drug discovery (Screening: HTS, FBDD, SBDD; Hit and lead validation)
- Antibody discovery (Immunization and display technologies)
- Clinical stage
Lactobionamide Surfactants with Hydrogenated, Perfluorinated or Hemifluorinated Tails
Lebaupain F. et al. 2006