Dopamine Receptor D3 (DRD3) Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A1556-20, A1556-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).
Synonyms: D3DR; ETM1; FET1; Dopamine Receptor D3 (DRD3)
GeneID: 1814
Swiss-Prot: P35462
Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB, IF/ICC
Calculated Molecular Weight: 44kDa
Observed Molecular Weight: 44kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 213-329 of human Dopamine Receptor D3 (Dopamine Receptor D3 (DRD3)) (NP_000787.2).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Research Areas: Neuroscience
Recommended Dilutions: WB: 1:500 - 1:2000 | IF/ICC: 1:50 - 1:200
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Cell Membrane, Multi-pass Membrane Protein
Positive Samples: Mouse brain
Keywords: 1814, sc-9185, sc-33921, sc-33922, sc-9184, sc-9114, DRD3, D3DR, ETM1, FET1, dopamine receptor D3, D(3) dopamine receptor, essential tremor 1, P35462, Drd3, Dopamine Receptor D3, D(3) Dopamine Receptor, Dopamine D3 Receptor, Essential Tremor 1, sc9185, sc 9185, sc33921, sc 33921, sc33922, sc 33922, sc9184, sc 9184, sc9114, sc 9114, Dopamine Receptor D3 (DRD3)
Symbol: DRD3
Category: Polyclonal Antibodies
Research Use Only