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Hemoglobin subunit alpha (HBA1) Rabbit pAb - A7322

Hemoglobin subunit alpha (HBA1) Rabbit pAb - A7322

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Hemoglobin subunit alpha (HBA1) Rabbit pAb

Sizes: 20µl, 100µl

Catalogue Numbers: A7322-20, A7322-100

Citations, Manuals and SDS Available upon request.

Background: The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.

Synonyms: HBH; ECYT7; HBA-T3; METHBA; Hemoglobin subunit alpha (HBA1)

GeneID: 3039

Swiss Prot: P69905

Tested Applications: ELISA, WB

Reactivity: Human, Mouse, Rat

Calculated Molecular Weight: 15kDa

Observed Molecular Weight: 14kDa/25kDa

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human Hemoglobin subunit alpha (Hemoglobin subunit alpha (HBA1)) (NP_000508.1).

Immunogen Species: Human

Host: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Recommended Dilutions: WB: 1:500 - 1:2000

Modifications: Unmodified

Conjugate: Unconjugated

Positive Samples: MCF7, Mouse liver, Mouse blood cells, Rat liver, Rat blood cells

Cellular Location: blood microparticle, Cytosol, Extra Cellular Exosome, Extra Cellular Region, Extra Cellular Space, hemoglobin Complex

Keywords: 3039, Alpha globin, HBA1, HBA2, Hemoglobin a, Hemoglobin alpha chain, Hemoglobin subunit alpha, hemoglobin, alpha 1, HBA-T3, HBH, hemoglobin subunit alpha 1, hemoglobin subunit alpha, alpha one globin, alpha-2 globin chain, delta globin, hemoglobin alpha 1 globin chain, P69905, Hemoglobin Subunit Alpha 1, Hemoglobin, Alpha 1, Hemoglobin Alpha 1 Globin Chain, Hemoglobin Subunit Alpha, Hemoglobin Alpha Chain, Alpha-2 Globin Chain, Alpha Globin Chain, Alpha One Globin, Delta Globin, Alpha-Globin, METHBA, HBAT3, HBA T3, Hemoglobin subunit alpha (HBA1)

Symbol: HBA1

Category: Polyclonal Antibodies

Research Use Only