JAM-A/CD321/F11R Rabbit PolymAb®
Sizes: 20μL, 100μL
Catalogue Numbers: A23909PM-20, A23909PM-100
Citations, Manuals and MSDS Available upon request.
Background: Predicted to enable PDZ domain binding activity; integrin binding activity; and protein homodimerization activity. Involved in intestinal absorption; regulation of cytokine production; and regulation of membrane permeability. Acts upstream of or within cell adhesion and epithelial cell differentiation. Located in bicellular tight junction. Is expressed in several structures, including 4-8 cell stage embryo; alimentary system; respiratory system; sensory organ; and urinary system. Human ortholog (s) of this gene implicated in hypertension. Orthologous to human F11R (F11 receptor) .
Category: Monoclonal Antibodies
Applications: WB, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 32kDa
Observed Molecular Weight: 40kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human/Mouse
GeneID: 50848/16456
SWISS: Q9Y624/O88792
Alternate Names: JAM; Jcam; JAM-1; JAM-A; Jcam1; Ly106; ESTM33; 9130004G24; JAM-A/CD321
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:5500 - 1:11000 IF/ICC, 1:100 - 1:400 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Cell Adhesion, Tight Junctions, Cytoskeleton, Immunology Inflammation, CDs, Cardiovascular, Blood.
NCBI Alias: CD321
Research Use Only