[KO Validated] YAP1 Rabbit mAb - A21216

[KO Validated] YAP1 Rabbit mAb

Sizes: 20µl, 100µl

Catalogue Numbers: A21216-20, A21216-100

Citations, Manuals and SDS Available upon request.

Background: This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms: YAP; YKI; COB1; YAP2; YAP-1; YAP65; P1

GeneID: 10413

Swiss-Prot: P46937

Reactivity: Human, Mouse, Rat

Tested Applications: ELISA, WB, IHC-P, IP, IF/ICC, ChIP

Calculated Molecular Weight: 54kDa

Observed Molecular Weight: 73kDa

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 155-504 of human YAP1 (NP_001123617.1).

Immunogen Species: Human

Host: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.

Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Protein phosphorylation, Cancer, Signal Transduction, Kinase, Tyrosine kinases, Cell Biology Developmental Biology

Recommended Dilutions: WB: 1:2000 - 1:20000 | IHC-P: 1:100 - 1:500 | IP: 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells | IF/ICC: 1:50 - 1:200 | ChIP: 5μg antibody for 10μg-15μg of Chromatin

Modifications: Unmodified

Conjugate: Unconjugated

Cellular Location: Cytoplasm, Nucleus

Positive Samples: HeLa, Mouse heart, C6

Keywords: 10413, sc-17140, sc-17141, sc-15407, 65 kDa Yes associated protein, YAP, YAP1, YAP2, YAP65, YKI, Yorkie homolog, COB1, Yes associated protein 1, transcriptional coactivator YAP1, 65 kDa Yes-associated protein, protein yorkie homolog, yes-associated protein 1, yes-associated protein 2, yes-associated protein YAP65 homolog, yorkie homolog, P46937, Yes Associated Protein 1, Yes-Associated Protein YAP65 Homolog, Yes-Associated Protein 1, Protein Yorkie Homolog, Transcriptional Coactivator YAP1, 65kDa, 65 KDa Yes-Associated Protein, Yes-Associated Protein 2, Yorkie Homolog, P1

Symbol: YAP1

Category: Monoclonal Antibodies

Research Use Only