Mannose Receptor/CD206 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A25433-20, A25433-100
Citations, Manuals and SDS Available upon request.
Background: The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.
Synonyms: MMR; hMR; CD206; MRC1L1; CLEC13D; CLEC13DL; bA541I19.1
GeneID: 4360
Swiss-Prot: P22897
Reactivity: Human, Rat
Tested Applications: ELISA, WB, IF/ICC
Calculated Molecular Weight: 166kDa
Observed Molecular Weight: 170-250kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 19-1389 of human Mannose Receptor/CD206 (NP_002429.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Research Areas: Immunology Inflammation, CDs, Cell Intrinsic Innate Immunity Signaling Pathway
Recommended Dilutions: WB: 1:500 - 1:1000 | IF/ICC: 1:50 - 1:200
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Cell Membrane, Endosome Membrane, Single-pass Type I Membrane Protein
Positive Samples: 293T transfected with MRC1/CD206
Keywords: 4360,sc-34577,sc-48758,CD206,CLEC13D,Macrophage mannose receptor 1,Mannose receptor,mannose receptor,C type 1,MMR,MRC1,CLEC13DL,MRC1L1,bA541I19.1,hMR,mannose receptor C-type 1,macrophage mannose receptor 1,C-type lectin domain family 13 member D,human mannose receptor,macrophage mannose receptor 1-like protein 1,C type 1-like 1,P22897,Mannose Receptor C-Type 1,Macrophage Mannose Receptor 1-Like Protein 1,C-Type Lectin Domain Family 13 Member D,Mannose Receptor,C Type 1-Like 1,Human Mannose Receptor,HMR,C-Type Lectin Domain Family 13 Member D-Like,Macrophage Mannose Receptor 1,Macrophage Mannose Receptor,C Type 1,CD206 Antigen,BA541I19.1
Symbol: MRC1
Category: Polyclonal Antibodies
Research Use Only