NCOR2 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A8388-20, A8388-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.
Synonyms: SMRT; TRAC; CTG26; SMRTE; TRAC1; N-CoR2; TNRC14; TRAC-1; SMAP270; SMRTE-tau; NCOR2
GeneID: 9612
Swiss-Prot: Q9Y618
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 274kDa
Observed Molecular Weight: 275kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-113 of human NCOR2 (NP_006303.4).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000 | IHC-P: 1:50 - 1:200
Research Areas: Epigenetics Nuclear Signaling, Nuclear Receptor Signaling, Nuclear hormone receptors, Cancer, Signal Transduction, ErbB-HER Signaling Pathway, Cell Biology Developmental Biology, Endocrine Metabolism, Lipid Metabolism
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HeLa, LO2
Cellular Location: Nucleus
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.