P53 mouse mAb (PT0337)
Sizes: 50µl, 100µl
Catalogue Numbers: RA11790-50, RA11790-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Store at: -20°C/1 year
Recommended Dilution: IHC-p 1:100-300，WB 1:500-2000
Purification Technology: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Alternative Names: Cellular tumor antigen p53 (Antigen NY-CO-13, Phosphoprotein p53, Tumor suppressor p53)
Background: tumor protein p53 (TP53) Homo sapiens This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013],
Applications: IHC-p, IF (paraffin section), WB
Species Cross-Reactivity: Human
GeneID (Human): 7157
SWISS: P04637
Source: Mouse
Immunogen: Synthesized peptide derived from human P53
Category: Monoclonal
Research Use Only