pan-Trk Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A23241-20, A23241-100
Citations, Manuals and SDS Available upon request.
Background: Neurotrophic tyrosine kinase (NTRK) is a family of receptor tyrosine kinase.The NTRK gene family contains three members, NTRK1, NTRK2 and NTRK3, which produce TRKA, TRKB and TRKC proteins, respectively.TRK kinases leads to cell differentiation and may play important roles in normal neural functions.Rearrangements in the NTRK genes can result in two genes fusing together and producing altered TRK proteins, which can lead to uncontrolled growth of cancer cells. Neurotrophic tyrosine receptor kinase (NTRK) gene fusions are an actionable biomarker for cancer therapy and can be found in over 25 different types of cancer.
GeneID: 4914/4915/4916
Swiss Prot: P04629/Q16620/Q16288
Tested Applications: ELISA, WB
Reactivity: Human, Mouse, Rat
Observed Molecular Weight: 120-140kDa
Immunogen: A synthesized peptide derived from human pan-Trk.
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: SH-SY5Y, Mouse brain, Rat brain
Cellular Location: Axon, Dendrite, Early Endosome, Late Endosome, Plasma Membrane
Symbol: pan-Trk
Category: Monoclonal Antibodies
Research Use Only