PAR2 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A5103-20, A5103-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a member of the G-protein coupled receptor 1 family of proteins. The encoded cell surface receptor is activated through proteolytic cleavage of its extracellular amino terminus, resulting in a new amino terminus that acts as a tethered ligand that binds to an extracellular loop domain. Activation of the receptor has been shown to stimulate vascular smooth muscle relaxation, dilate blood vessels, increase blood flow, and lower blood pressure. This protein is also important in the inflammatory response, as well as innate and adaptive immunity.
Synonyms: PAR2; GPR11
GeneID: 2150
Swiss-Prot: P55085
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 44kDa
Observed Molecular Weight: 55kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 298-397 of human PAR2 (P55085).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000 | IHC-P: 1:50 - 1:200
Research Areas: Signal Transduction, G protein signaling, G-Protein-Coupled Receptors (GPCR)
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HCT 116, Hep G2, BxPC-3, Mouse large intestine, Rat large intestine
Cellular Location: Cell Membrane, Multi-pass Membrane Protein
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.