PCK1 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A22172-20, A22172-100
Citations, Manuals and SDS Available upon request.
Background: This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.
Synonyms: PCKDC; PEPCK1; PEPCKC; PEPCK-C; PCK1
GeneID: 5105
Swiss-Prot: P35558
Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB
Calculated Molecular Weight: 69kDa
Observed Molecular Weight: 69kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 523-622 of human PCK1 (NP_002582.3).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Research Areas: Cancer, Signal Transduction, Endocrine Metabolism, Lipid Metabolism, Cholesterol Metabolism, Carbohydrate metabolism, Endocrine and metabolic diseases, Diabetes, Cardiovascular, Heart, Lipids, Cardiovascular diseases, Heart disease
Recommended Dilutions: WB: 1:1000 - 1:5000
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Cytoplasm
Positive Samples: Hep G2, Mouse kidney, Rat kidney
Keywords: 5105, sc-74825, sc-130843, sc-74823, sc-135278, PCK1, PEPCK C, PEPCK1, PEPCKC, Phosphoenolpyruvate carboxykinase 1, PEPCK-C, phosphoenolpyruvate carboxykinase 1, phosphoenolpyruvate carboxykinase, cytosolic [GTP], PEP carboxykinase, phosphoenolpyruvate carboxykinase 1 (soluble), cytosolic, phosphoenolpyruvate carboxylase, phosphopyruvate carboxylase, P35558, Phosphoenolpyruvate Carboxykinase 1, Phosphoenolpyruvate Carboxykinase 1 (Soluble), Phosphoenolpyruvate Carboxykinase, Cytosolic [GTP], Cytosolic, Phosphoenolpyruvate Carboxylase, Phosphopyruvate Carboxylase, PEP Carboxykinase, EC 4.1.1.32, PCKDC, MGC22652, sc74825, sc 74825, sc130843, sc 130843, sc74823, sc 74823, sc135278, sc 135278
Symbol: PCK1
Category: Monoclonal Antibodies
Research Use Only