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PDIA6 Rabbit mAb - A4260

PDIA6 Rabbit mAb - A4260

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$168.00 USD
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PDIA6 Rabbit mAb

Sizes: 20µl, 100µl

Catalogue Numbers: A4260-20, A4260-100

Citations, Manuals and SDS Available upon request.

Background: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, a TRX-like domain, and a C-terminal ER-retention sequence. This protein inhibits the aggregation of misfolded proteins and exhibits both isomerase and chaperone activity. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms: P5; ERP5; TXNDC7; PDIA6

GeneID: 10130

Swiss-Prot: Q15084

Reactivity: Human, Mouse, Rat

Calculated Molecular Weight: 48kDa

Observed Molecular Weight: 50kDa

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PDIA6 (NP_005733.1).

Immunogen Species: Human

Host: Rabbit

Isotype: IgG

Purity: Affinity purification

Tested Applications: ELISA, WB, IF/ICC

Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.

Recommended Dilutions: WB: 1:500 - 1:2000 | IF/ICC: 1:50 - 1:200

Research Areas: Signal Transduction

Modifications: Unmodified

Conjugate: Unconjugated

Positive Samples: HeLa, Hep G2, Mouse liver, Rat liver

Cellular Location: Cell Membrane, Endoplasmic Reticulum Lumen, Melanosome

Category: Monoclonal Antibodies

Citations, Manuals and SDS Available upon request.