PE-Cy5 Anti-Human TCR Vα24-Jα18 Antibody (6B11)
Sizes: 20T, 100T
Catalogue Numbers: PC5-30292-20, PC5-30292-100
Citations, Manuals and MSDS Available upon request.
Target: Human TCR Vα24
Form: Liquid
Conjugation: PE-Cy5
Conjugation Information: PE-Cy5 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 670 nm (e.g., a 690/50 nm bandpass filter).
Host: Mouse
Clonality: Monoclonal
Clone ID: 6B11
Isotype: IgG1
Storage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Encoded by the TCR Vα24-Jα18 germline configuration, Vα24-JαQ is expressed on a subset of NKT cells, namely invariant NKT (iNKT). Vα24-JαQ TCR interacts with the glycolipid loaded MHC class 1b molecule CD1d, inducing activation and subsequent cytokine production. iNKT cells have been implicated in immune regulation, tumor surveillance, and host response to pathogens. While iNKT cells occur at low frequency in the blood, assorted chemokines contribute to their tissue homing potential.
Synonyms: TCR Vα24-Jα18|TCR Vα24-JαQ|invariant NKT cell|iNKT
Reactivity: Human
Tested Application: FC
Recommended Dilution: Volume per test: 5μL. Each lot of this antibody is quality control tested by Flow cytometryometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Gene ID: 28659
Category: Flow cytometryometry Antibodies
Research Use Only