Pepsinogen I (PG I) Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A23155-20, A23155-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer.
Synonyms: Pepsinogen-4; Pepsinogen I (PG I)
GeneID: 643847
Swiss Prot: P0DJD7
Tested Applications: ELISA, IHC-P, IF/ICC
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 42kDa
Observed Molecular Weight: Refer to figures
Immunogen: Recombinant protein of human Pepsinogen I (PG I).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: IHC-P: 1:50 - 1:200 | IF/ICC: 1:50 - 1:200
Research Areas: Ubiquitin, Endocrine Metabolism
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Secreted
Keywords: Pepsinogen-4; Pepsinogen I (PG I)
Symbol: PGA4
Category: Monoclonal Antibodies
Research Use Only