PER3 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A2219-20, A2219-100
Citations, Manuals and SDS Available upon request.
Background: This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been linked to sleep disorders. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms: GIG13; FASPS3; PER3
GeneID: 8863
Swiss-Prot: P56645
Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB
Calculated Molecular Weight: 132kDa
Observed Molecular Weight: 132kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 10-100 of human PER3 (P56645).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Endocrine Metabolism, Cardiovascular, Heart, Cardiogenesis
Recommended Dilutions: WB: 1:500 - 1:1000
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Cytoplasm, Nucleus
Positive Samples: HeLa, Mouse lung, Mouse kidney, Rat lung
Keywords: PER3, FASPS3, GIG13, period circadian clock 3, period circadian protein homolog 3|cell growth-inhibiting gene 13 protein|circadian clock protein PERIOD 3|hPER3|period circadian protein 3, P56645
Symbol: PER3
Category: Monoclonal Antibodies
Research Use Only