PEX19 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A19237-20, A19237-100
Citations, Manuals and SDS Available upon request.
Background: This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.
Synonyms: PXF; HK33; PMP1; PMPI; PXMP1; PBD12A; D1S2223E; PEX19
GeneID: 5824
Swiss-Prot: P40855
Reactivity: Human
Tested Applications: ELISA, WB
Calculated Molecular Weight: 33kDa
Observed Molecular Weight: 35kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PEX19 (P40855).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Research Areas: Signal Transduction
Recommended Dilutions: WB: 1:500 - 1:1000
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Cytoplasm, Cytoplasmic Side, Lipid-anchor, Peroxisome Membrane
Positive Samples: HeLa, K-562
Keywords: sc-18791, 33 kDa housekeeping protein, D1S2223E, HK33, Peroxin 19, PEX19, PMP1, PMPI, PXF, PXMP1, PBD12A, peroxisomal biogenesis factor 19, housekeeping gene, 33kD, peroxin-19, peroxisomal farnesylated protein, P40855, 5824, sc18791, sc 18791, Unconjugated
Symbol: PEX19
Category: Monoclonal Antibodies
Research Use Only