PGC1 beta Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A4331-20, A4331-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene.
Synonyms: PERC; ERRL1; PGC1B; PGC-1(beta); PGC1 beta
GeneID: 133522
Swiss-Prot: Q86YN6
Reactivity: Human, Rat
Calculated Molecular Weight: 113kDa
Observed Molecular Weight: 113kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 924-1023 of human PGC1 beta (NP_573570.3).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000
Research Areas: Epigenetics Nuclear Signaling, Nuclear Receptor Signaling, Endocrine Metabolism, Mitochondrial metabolism, Mitochondrial markers, Endocrine and metabolic diseases, Diabetes, Cardiovascular, Lipids, Fatty Acids
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HeLa, SH-SY5Y, Rat testis
Cellular Location: Cytosol, Mitochondrion, Nucleoplasm, Nucleus
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.