Phospho-IκBα-S32 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: AP1220-20, AP1220-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.
Synonyms: IKBA; MAD-3; NFKBI; EDAID2; Phospho-IκBα-S32
GeneID: 4792
Swiss-Prot: P25963
Reactivity: Human, Mouse
Calculated Molecular Weight: 36kDa
Observed Molecular Weight: 40kDa
Immunogen: A synthetic phosphorylated peptide around S32 of human NFKBIA (NP_065390.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000
Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Protein phosphorylation, Cancer, Signal Transduction, MAPK-Erk Signaling Pathway, ATM Signaling Pathway, Cell Biology Developmental Biology, Apoptosis, Inhibition of Apoptosis, Death Receptor Signaling Pathway, Immunology Inflammation, B Cell Receptor Signaling Pathway, T Cell Receptor Signaling Pathway, NF-kB Signaling Pathway, Toll-like Receptor Signaling Pathway, Cell Intrinsic Innate Immunity Signaling Pathway, TLR Signaling
Modifications: Phospho S32
Conjugate: Unconjugated
Positive Samples: HeLa, NIH/3T3
Cellular Location: Cytoplasm, Nucleus
Category: Phosphorylated Antibodies
Citations, Manuals and SDS Available upon request.