Phospho-Tau-Ser202/Thr205 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: AP0894-20, AP0894-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Synonyms: TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; tau-40; FTDP-17; PPP1R103; Tau-PHF6; Phospho-Tau-Ser202/Thr205
GeneID: 4137
Swiss-Prot: P10636-5
Reactivity: Human, Mouse
Calculated Molecular Weight: 79kDa
Observed Molecular Weight: 50-80kDa
Immunogen: A synthetic phosphorylated peptide around S202 & T205 of human Tau (NP_058519.3?).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000
Research Areas: Protein phosphorylation, Signal Transduction, Cell Biology Developmental Biology, Apoptosis, Cytoskeleton, Microtubules, Neuroscience, Cell Type Marker, Neurodegenerative Diseases, Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease, Stem Cells, Neuron marker
Modifications: Phospho S202/T205
Conjugate: Unconjugated
Positive Samples: HeLa
Cellular Location: Cell Membrane, Cell Projection, Cytoplasm, Cytoplasmic Side, Peripheral Membrane Protein, Axon, Cytoskeleton, Cytosol
Category: Phosphorylated Antibodies
Citations, Manuals and SDS Available upon request.