PLA2G2A Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A19252-20, A19252-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.
Synonyms: MOM1; PLA2; PLA2B; PLA2L; PLA2S; PLAS1; sPLA2; PLA2G2A
GeneID: 5320
Swiss-Prot: P14555
Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB
Calculated Molecular Weight: 16kDa
Observed Molecular Weight: 15kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 65-144 of human PLA2G2A (P14555).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Research Areas: Cancer, Signal Transduction, Cell Biology Developmental Biology, Cell Cycle, Centrosome, Endocrine Metabolism, Lipid Metabolism, Lipases, Cardiovascular, Lipids
Recommended Dilutions: WB: 1:500 - 1:1000
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Membrane, Peripheral Membrane Protein
Positive Samples: HT-29, HepG2, DU145, Mouse liver, Mouse spleen, Mouse small intestine, Rat spleen, Rat small intestine, Rat liver
Keywords: sc-14467, sc-14468, sc-20105, PLA2G2A, MOM1, PLA2, PLA2B, PLA2L, PLA2S, PLAS1, sPLA2, phospholipase A2 group IIA, phospholipase A2, membrane associated, GIIC sPLA2, NPS-PLA2, group IIA phospholipase A2, non-pancreatic secretory phospholipase A2, phosphatidylcholine 2-acylhydrolase 2A, group IIA (platelets, synovial fluid), P14555, 5320, sc14467, sc 14467, sc14468, sc 14468, sc20105, sc 20105, Unconjugated
Symbol: PLA2G2A
Category: Monoclonal Antibodies
Research Use Only