Placental alkaline phosphatase (PLAP) Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A4304-20, A4304-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. One of the main sources of this enzyme is the liver, and thus, it's one of several indicators of liver injury in different clinical conditions. In pregnant women, this protein is primarily expressed in placental and endometrial tissue, however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells.
Synonyms: ALP; IAP; ALPI; PALP; PLAP; PLAP-1; Placental alkaline phosphatase (PLAP)
GeneID: 250
Swiss-Prot: P05187
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 58kDa
Observed Molecular Weight: 70kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Placental alkaline phosphatase (PLAP) (P05187).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IHC-P: 1:500 - 1:1000
Research Areas: Stem Cells
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: PC-3 cells, Mouse testis
Cellular Location: Cell Membrane, GPI-anchor, Lipid-anchor
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.