PMPCA Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A24606-20, A24606-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene is found in the mitochondrion, where it represents the alpha subunit of a proteolytic heterodimer. This heterodimer is responsible for cleaving the transit peptide from nuclear-encoded mitochondrial proteins. Defects in this gene are a cause of spinocerebellar ataxia, autosomal recessive 2.
Synonyms: CLA1; CPD3; MAS2; P-55; SCAR2; INPP5E; Alpha-MPP; PMPCA
GeneID: 23203
Swiss-Prot: Q10713
Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB, IHC-P, IP
Calculated Molecular Weight: 55kDa
Observed Molecular Weight: 58kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 291-525 of human PMPCA (NP_055975.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Ubiquitin, Endocrine Metabolism, Mitochondrial metabolism
Recommended Dilutions: WB: 1:1000 - 1:5000 | IHC-P: 1:100 - 1:500 | IP: 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Mitochondrion Matrix, Mitochondrion Inner Membrane
Positive Samples: HeLa, MCF7, Mouse placenta, Rat thymus
Keywords: 23203, PMPCA, Alpha-MPP, INPP5E, P-55, SCAR2, peptidase, mitochondrial processing alpha subunit, mitochondrial-processing peptidase subunit alpha, inositol polyphosphate-5-phosphatase, 72 kD, mitochondrial matrix processing protease, alpha subunit, Q10713, Spinocerebellar Ataxia, Autosomal Recessive 2, Cerebellar Ataxia 1 (Autosomal Recessive), P55, P 55, AlphaMPP, Alpha MPP
Symbol: PMPCA
Category: Monoclonal Antibodies
Research Use Only